brief description about regulations and laboratory animal science
Animal Welfare Act
Protects all warm-blooded animals except rats, mice, and birds bred for research. This includes zoos, circuses, research labs, hospitals, businesses, federal agencies, dealers, breeders, etc.
Each research institution that uses a covered species must have an IACUC review all animal experiment protocols. The USDA licenses research facilities and conducts annual, unannounced inspections. Violations are punished with fines, cease-and-desist orders, and license suspension or revocation.
Protects all vertebrate animals (including fish, reptiles, rats, mice, and birds) used in research funded by the Public Health Service. Each research facility provides a written plan for complying with PHS Policy and the Guide. Each research institution that receives PHS funding must have the IACUC review all animal experimental protocols and inspect the facilities. No routine, unannounced inspections, but all allegations of misuse are investigated by NIH's Office of Laboratory Animal Welfare. Violations or loss of AAALAC accreditation can result in loss of PHS funding.
A committee, organized at every research facility subject to the AWA, PHS Policy, or AAALAC accreditation, which must review and approve or deny every proposed animal protocol. Each animal protocol must include:
—A justification for using animals, the number of animals to be used, and the species chosen
—The procedures or drugs to be used to eliminate or minimize pain and discomfort
—A description of the methods and sources used to search for alternative to painful procedures
—A description of the search used to ensure that the experiment does not unnecessarily duplicate previous research
Members must include: a veterinarian, a professional not involved in research (ethicist, lawyer, etc.), and a community representative (clergy, teacher, etc.). IACUC members must inspect their research facility twice a year.